Abstract

Cryopreservation of ovarian tissue is a potential alternative or addition to cryopreservation of embryos or oocytes for sustaining fertility in women at risk of premature ovarian failure. Grafts of cryopreserved ovarian tissue have resulted in live-born mice and sheep. While human applications are in their infancy, frozen human ovarian tissue grafted to the kidney capsules of immunodeficient mice has produced normally developing ovarian follicles.

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