Abstract
Objective: To compare the outcome of vitrification versus slow freezing cryopreservation for cleavage stage day 2–3 embryos.Design: A retrospective observational study.Setting: All thawed embryos assisted reproduction cycles between January 2010 and December 2012 at a single IVF laboratory of a Tertiary Medical Center.Patients: Five hundred and thirty-nine cycles of day 2–3 thawed embryos.Interventions: In 327 of the thawed cycles, the embryos were vitrified and in 212 of the cycles the embryos were derived from slow freezing embryos.Main outcomes measure: Embryo survival rate, blastomere surviving rate and pregnancy rate.Results: Embryo survival rate was significantly higher after vitrification compared with slow freezing (81.6%, 647/793 versus 70.0%, 393/562 embryos, p < 0.0001). The clinical pregnancy rate per ET was significantly higher following vitrification compared to slow freezing, 20.0%, 63/314 versus 11.9%, 23/193, respectively (p = 0.02).Conclusions: Vitrification of day 2–3 cleavage stage embryos yields better cycle outcome in all the parameters compared to slow freezing.
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
