Abstract

Meeting abstracts Antigen-specific DNA vaccine immunotherapy is an attractive approach for the treatment of cancer since it has the potency to specifically eradicate systemic tumors without damaging the normal cells. However, DNA vaccine shows insufficient immune response for antigen presenting

Highlights

  • Antigen-specific DNA vaccine immunotherapy is an attractive approach for the treatment of cancer since it has the potency to eradicate systemic tumors without damaging the normal cells

  • Cryoablation therapy stimulates the antigenspecific T cell immune responses generated by therapeutic HPV DNA vaccine

  • The mice were divided into four groups: group 1 received no treatment after the E7-expressing TC-1 tumor challenge, group 2 was treated with cryoablation therapy, group 3 was immunized with the CRT/E7 DNA vaccine, and group 4 was both immunized and received cryoablation therapy

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Summary

Introduction

Antigen-specific DNA vaccine immunotherapy is an attractive approach for the treatment of cancer since it has the potency to eradicate systemic tumors without damaging the normal cells. Cryoablation therapy stimulates the antigenspecific T cell immune responses generated by therapeutic HPV DNA vaccine From 30th Annual Meeting and Associated Programs of the Society for Immunotherapy of Cancer (SITC 2015) National Harbor, MD, USA.

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