Abstract
In the last decade the field of Structural Biology has made great advances in using electron microscopy to solve structures of protein complexes including membrane proteins to high resolution. Best practices of how to use Single Particle Cryo-EM and more importantly how to optimize a membrane protein sample such as an ion channel or a transporter will be discussed. Most membrane protein structures are currently resolved in a detergent micelle, but cryo-EM also makes it possible to look at membrane protein complexes in a lipid bilayer, such as a lipid nanodisc, liposomes, or even inside cells now.
Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
