Abstract
This study was conducted to determine the activity of the methanolic crude extracts collected from the seeds and rinds of native durian (Durio zibethinus) against hospital isolates of Escherichia coli and Staphylococcus aureus. The fruit samples were collected from a local durian dealer and subjected to rotary evaporator. Using the Kirby-Bauer disc diffusion technique, the crude extracts with different concentrations (100, 75, 50 and 25%) were tested against the two isolates and after 24 h of incubation, zones of inhibition were measured. Durian seed and rind exhibits greater inhibition on the E. coli bacterium with inhibitions greater than chloramphenicol, which is the positive control.
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