Abstract

Aims: This study was embarked upon to determine the effect of diabetes mellitus on food intake, water intake and body weight, and to ascertain the impact of treatment with crudeAloe veragel on diabetic animals. Methodology: The phyto-constituents and median lethal dose of crude Aloe veragel were determined before administration. 32 albino wistar rats were divided into four groups thus, control, diabetic untreated group (DM), diabetic gr oup treated with crude Aloe veragel (DMT) and crudeAloe veragel treated control group. Food intake, water intake, body weight and fasting blood glucose levels were measured during the research work. Results:Food intake, water intake, and fasting blood glucose levels were significantly (P<0.001) increased in DM group compared to control, DMT and CT group. Body weight was significantly ( P<0.001) increased in CT group compared to control. DM group had a significantly ( P<0.001) lower body weight compared tocontrol, DMT ( P<0.001) and CT

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