Abstract
Abstract 3-Bromoacetyl-6,7-[2′,3′-(1′,4′,7′,10′,13′-pentaoxacyclopentadeca)-2′-ene]coumarin (2) was prepared as a new fluorescence derivatization reagent for carboxylic acids in high-performance liquid chromatographic analysis. The derivatization of lauric acid with 2 was readily accomplished under a quite mild condition to yield a highly fluorescent lauric acid derivative. The reaction was accelarated by combining crown moiety as a catalytic site to coumarin fluorophore.
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