Abstract

Meeting abstracts The lymphatic system serves as the primary route for the metastasis of many cancers and the extent of lymphangiogenesis involvement is the most important indicator of tumor aggressiveness. Despite the apparent importance of the lymphatic vessels for tumor dissemination, it has

Highlights

  • The lymphatic system serves as the primary route for the metastasis of many cancers and the extent of lymphangiogenesis involvement is the most important indicator of tumor aggressiveness

  • Our data suggest that lymphangiogenesis can be targeted therapeutically at different stages, and by different way

  • Inflammatory lymph node lymphangiogenesis is a multi step process defined by initiation, expansion and a return to quiescence

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Summary

Introduction

The lymphatic system serves as the primary route for the metastasis of many cancers and the extent of lymphangiogenesis involvement is the most important indicator of tumor aggressiveness. Elhadad Journal for ImmunoTherapy of Cancer 2013, 1(Suppl 1):P184 http://www.immunotherapyofcancer.org/content/1/S1/P184 Cross talks between the immune and lymphatic endothelial cells regulate inflammatory lymph node lymphangiogenesis: defining a new therapeutic approach From Society for Immunotherapy of Cancer 28th Annual Meeting National Harbor, MD, USA.

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