Cross sectional study of the relationship between the presence / severity of coronary artery disease evaluated by computed tomography coronary angiography and the presence/ degree of non-alcoholic fatty liver disease evaluated by trans-abdominal ultrasonography

Abstract

Abstract Background Coronary artery disease is one of the common causes of mortality worldwide. Studies have shown a prevalence of 24.5% in Egypt. Therefore, early accurate diagnosis, risk factors and associations of coronary artery disease are of utmost importance. Objectives The aim of the current study is to investigate the relationship between the presence / severity of coronary artery disease and presence extent of nonalcoholic fatty liver disease. Patients and Methods Cross-sectional study on total 52 patients performed multi-slice computed tomography coronary angiography, and liver evaluation by abdominal ultrasonography at Dar Shefaa hospital. Results We found that there is a positive significant relationship between the number of coronary arteries affected and the coronary lesion degree of stenosis (proven by P value= 0.909). Also, a positive significant relationship between the number of affected vessels and the degree of non-alcoholic fatty liver disease (proven by P value =-0.783). Also, a positive significance between coronary lesion stenosis degree and the degree of non-alcoholic fatty liver disease (proven by P value= 0.785). Conclusion The existence of non-alcoholic fatty liver disease is independently associated with the presence and existence of coronary artery disease. it is not still clear whether the non-alcoholic fatty liver disease causes coronary artery disease or whether this relationship is seem because of the common mechanisms causing both diseases, yet the relationship between the existence of hepatosteatosis and the extent of coronary artery disease has been strongly documented.