“CROSS- SECTIONAL STUDY OF NON ALCOHOLIC FATTY LIVER DISEASE AND IT'S ASSOCIATION WITH CENTRAL OBESITY, DYSLIPIDEMIA AND IMPAIRED GLUCOSE TOLERANCE.”

Abstract

Introduction- Non alcoholic fatty liver disease (NAFLD) is dened as accumulation of fat in liver, mainly triglyceride in absence of other possible etiologies, such as viral hepatitis, signicant alcohol intake, autoimmune hepatitis or hepatotoxic drugs. Nonalcoholic fatty liver disease (NAFLD) has become the most common chronic liver disease in modern societies, affecting as many as 20% to 30% of general population worldwide [1]. Components of metabolic syndrome i.e central obesity, hyperglycemia, dyslipidemia, hypertension are major risk factors for NAFLD. The purpose of the present study is to nd an association of NAFLD with dyslipidemia, central obesity and impaired glucose tolerance, so that the patients can be timely managed and further risk of cardiovascular complications can be reduced. The aim of this study is toAims And Objectives- determine the prevalence of undetected central obesity, dyslipidemia and glucose intolerance in NAFLD patients. In 100Material And Methods- non alcoholic subjects with USG diagnosis of fatty liver, fasting blood sugar, postprandial blood sugar and HbA1C levels, fasting lipid prole were analysed. Waist circumference was measured and BMI calculated. Prevalence of dyslipidemia in NAFLD was 46%, prevalence ofResult- impaired glucose tolerance and diabetes was 36% and 3% respectively and prevalence of central obesity was 83%. There was a positive correlation between FBS and BMI tested by pearson's correlation test that was statistically signicant as P value was 0.046. In our study it isConclusion- found that prevalence of dyslipidemia, prediabetes and central obesity is signicantly higher in NAFLD cases, also there is a statistically signicant correlation between FBS and central obesity.