Abstract

The membrane teichoic acid (MTA) precipitates heavily in the equine and rabbit antipneumococcal (anti-Pn) type XII sera tested. MTA contains multiple kojibiosyl residues and this reaction confirms the presence of kojibiosyl residues in the capsular polysaccharide, S XII, the antigenic determinant of pneumococcal type XII. MTA also precipitates one-third of the antibodies in an anti-Pn XVI serum: the poly(glycerol phosphate) residues of MTA may be involved in this reaction as well as d-glucose residues. Precipitation of MTA in anti-Pn XII is strongly inhibited by kojibiose, but the reaction in anti-Pn XVI is unaffected.

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