Abstract

BackgroundDisability weights represent the relative severity of disease stages to be incorporated in summary measures of population health. The level of agreement on disability weights in Western European countries was investigated with different valuation methods.MethodsDisability weights for fifteen disease stages were elicited empirically in panels of health care professionals or non-health care professionals with an academic background following a strictly standardised procedure. Three valuation methods were used: a visual analogue scale (VAS); the time trade-off technique (TTO); and the person trade-off technique (PTO). Agreement among England, France, the Netherlands, Spain, and Sweden on the three disability weight sets was analysed by means of an intraclass correlation coefficient (ICC) in the framework of generalisability theory. Agreement among the two types of panels was similarly assessed.ResultsA total of 232 participants were included. Similar rankings of disease stages across countries were found with all valuation methods. The ICC of country agreement on disability weights ranged from 0.56 [95% CI, 0.52–0.62] with PTO to 0.72 [0.70–0.74] with VAS and 0.72 [0.69–0.75] with TTO. The ICC of agreement between health care professionals and non-health care professionals ranged from 0.64 [0.58–0.68] with PTO to 0.73 [0.71–0.75] with VAS and 0.74 [0.72–0.77] with TTO.ConclusionsOverall, the study supports a reasonably high level of agreement on disability weights in Western European countries with VAS and TTO methods, which focus on individual preferences, but a lower level of agreement with the PTO method, which focuses more on societal values in resource allocation.

Highlights

  • Disability weights represent the relative severity of disease stages to be incorporated in summary measures of population health

  • All summary measures of population health are built on three critical inputs: mortality by age, sex and condition; epidemiological data on non-fatal health outcomes by age, sex and condition; and valuations of health states that assess the relative severity of a year lived in a particular condition

  • We found that the agreement between people of similar academic background but of different medical background was good with visual analogue scale (VAS) and time trade-off (TTO), and sufficient with person trade-off technique (PTO)

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Summary

Introduction

Disability weights represent the relative severity of disease stages to be incorporated in summary measures of population health. Summary measures of population health combine information on mortality and non-fatal health outcomes in order to represent the health of a particular population as a single measure [1]. They are used traditionally for comparative judgements of average levels of population health between populations and over time. All summary measures of population health are built on three critical inputs: mortality by age, sex and condition; epidemiological data on non-fatal health outcomes by age, sex and condition; and valuations of health states (disability weights) that assess the relative severity of a year lived in a particular condition. Since the assumption of cross-national agreement on disability weights has been further supported by studies using similar valuation protocols [10,11], whereas agreement between different types of informants in health have shown contradictory results [12,13,14,15]

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