Cross-cultural validation of a short-form of the Vitiligo Impact Patient scale (VIPs)

Abstract

There is a lack of short-form questionnaires evaluating the burden of vitiligo according to skin phototype. To develop and validate a 12-item short-form of the Vitiligo Impact Patient scale (VIPs) that takes into account skin phototype. Multicenter, prospective, cross-sectional study conducted in France (Créteil and Bordeaux) and the US (Worcester, Massachusetts, and Dallas, Texas). In total, 891 patients completed the questionnaire. Of these, 509 patients belonged to the French Developmentsample-313 with dark skin (DS) (phototypes IV to VI) and 196 with fair skin (FS) (phototypes I to III). The US validation sample comprised 382 patients-113 DS and 269 FS. There was a very high correlation between VIPs-FS and its 12-item short-form, VIPs-12-FS, in both the development and validation samples (respectively, rho=0.96, P<.0001 and rho=0.98, P<.0001). Similarly, the correlations between VIPs-DS and its short-form, VIPs-12-DS, in both the development and validation samples were very high (respectively, rho=0.95, P<.0001 and rho=0.96, P<.0001). Responsiveness of the 12-item short-forms should be confirmed. These data enabled the development and validation of 12-item short-forms of the VIPs questionnaires for fair (VIPs-12-FS) and dark (VIPs-12-DS) skin.