Cross-cultural adaptation and validation with reliability, validity, and responsiveness of the Italian version of the Oxford Hip Score in patients with hip osteoarthritis

Abstract

The purpose of this study was to translate the Oxford Hip Score (OHS) into Italian and to evaluate the psychometric properties by testing the feasibility, internal consistency, reproducibility, construct validity, and responsiveness in patients with hip osteoarthritis (OA). The OHS Italian version was developed and evaluated in Italian-speaking patients with hip OA. The psychometric properties assessed were feasibility with floor and ceiling effect; internal consistency with Cronbach's Alpha; reproducibility with intraclass correlation coefficient (ICC); construct validity with evaluating correlation with the SF-36 and visual analogue scale (VAS) for pain; responsiveness to intra-articular hyaluronate injections. The standardized effect size (ES) and standardized response mean (SRM) were also evaluated. A total of 96 patients were recruited (mean age 62.7±5.8years, range 49-77). No floor or ceiling effect was observed prior to or after treatment with HA injections. Cronbach's alpha value was 0.85 at baseline and 0.89 after treatment. The reproducibility was good with an ICC of 0.89. A strong correlation was found between OHS, VAS, and some SF-36 subscales, indicating good cross-sectional and longitudinal construct validity. The mean OHS improved from 16.4±5.8 to 28.0±9.0 after hyaluronate injections (P<0.01). The ES and SRM values were 1.98 and 1.12, respectively. The Italian OHS questionnaire is valid, reliable, and responsive for use in Italian patients with symptomatic hip OA receiving hyaluronate injections.