Abstract
Massive gastrointestinal bleeding (GIB) is a rare complication of Crohn’s disease (CD). For the recent decades a number of medical and surgical methods to control the GIB have been introduced. However, the unified algorithm and approach to this subset of patients is still lacking, mostly due to the absence of adequately powered and wellconducted RCTs. Determining the optimal treatment approach to inflammatory bowel disease (IBD) in patients who develop a GIB is still a valid research target.
Highlights
Markushin L.I. Crohn's disease manifested with massive colonic bleeding
Severe lower gastrointestinal bleeding in Crohn’s disease: successful control with infliximab
Summary
FOR CITATION: Atroshchenko A.O., Kolygin A.V., Severova M.M., Markushin L.I. Crohn’s disease manifested with massive colonic bleeding (review and a clinical case). В подавляющем большинстве случаев источники кровотечения располагаются в подвздошной или толстой кишке, что подтверждается при помощи эндоскопии или во время операции. Что применение цитостатиков-азатиоприна (АЗА) или 6-меркаптопурина (6-МП) может снижать риск развития ЖКК при БК — OR 0,53 (95% ДИ: 0,30–0,91) [3].
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