Abstract
Crohn’s disease (CD), which can be localized in any part of the gastrointestinal tract, is a disease characterized by an irregular immune response to normal and/or abnormal microbial antigens. Recent studies show many extensive data about the roles of genetic and environmental factors, immune function, and gut microbiota in CD. Although, less invasive biomarkers are currently being developed, the diagnosis of the disease is still based on the endoscopy and histological evaluation of biopsy samples. The most common symptoms are diarrhea, abdominal pain, weight loss, and fatigue. Despite the improvements in the treatment methods in the last decade, there is no definitive treatment since the etiology of CD is not known exactly. Therapeutic strategies focus on reducing inflammation and symptoms, maintaining clinical remission, and improving quality of life.
Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
