Critical Analysis of Cervical and Endometrial Biopsy Specimens

Abstract

Introduction: This is a retrospective study done in cervical and endometrial biopsy specimens received in the pathology department of Shree Birendra Hospital over a period of one year from 14th April, 2011 to 13th April, 2012. The aims of this study were to analyze the histological findings of cervical and endometrial biopsies and to identify activities needed to critically evaluate these specimens. Methods: The histopathological diagnoses of 104 cervical and 84 endometrial biopsy specimens reported by the pathologists were retrieved. The diagnoses were categorized and correlated with age in order to work out a strategy for better patient management. Results: The majority of 104 cervical biopsies (76.0%) comprised of neoplastic lesions and 83.5% of them were low-grade squamous intraepithelial lesions. Among the nonneoplastic lesions, cervical polyps and cervicitis were in the ratio of 3:2. Of the 84 endometrial biopsies analyzed, proliferative endometrium comprised the majority (61.9%) with disordered proliferative being the most common pattern. Detailed information about the patients was minimal including the absence of age in 8.0% of cases. More than 80% of both cervical and endometrial biopsies were performed in the age group 30-59 years of age. Conclusions: Neoplastic lesions comprised the majority of the cervical biopsies while all the endometrial biopsies were nonneoplastic. Important clinical information like age of the patient has to be mentioned in the biopsy request form for useful clinical correlation of histological findings. Medical Journal of Shree Birendra Hospital; January-June 2013/vol.12/Issue1/23-28DOI: http://dx.doi.org/10.3126/mjsbh.v12i1.9088