Abstract
In this review paper, the mechanism of HIV infection and some of the most efficacious and updated gene therapy methods developed by scientists will be discussed in detail. Different editing strategy using the CRISPR-Cas9 system inhibits different times of the HIV life cycle are involved with all the same target, which is to block the HIV infection pathway as well as its own replication&proliferation pathway. As the most popular and promising way of treating different kinds of diseases which seemed to be incurable in the past, and CRISPR-Cas9 shows high potency under the data of experiments and clinical studies. These give scientists many confidence to run out more research on this new treatment for diseases and at the same time to improve and optimize the function and efficiency of this gene editing toolkit making sure it can used widely in the future as an actual clinical treatment for the HIV/AIDS.
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