Abstract

CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) technology has revolutionized plant pathology by providing a precise and efficient tool for enhancing disease resistance in crops. This gene-editing technique enables scientists to modify specific DNA sequences in plants, allowing for the targeted improvement of traits related to pathogen defense. By altering genes responsible for susceptibility to diseases, CRISPR facilitates the development of crops that are more resistant to bacterial, fungal, and viral pathogens, thereby reducing the reliance on chemical pesticides. Additionally, CRISPR can be used to boost plant immunity and improve resilience against emerging plant diseases that threaten global food security. The technology's accuracy and speed have accelerated breeding programs, enabling researchers to respond rapidly to agricultural challenges posed by climate change and the evolution of new pathogens. This article explores the breakthroughs achieved through CRISPR in plant pathology, highlighting case studies of its application in major crops such as rice, wheat, and tomatoes. Furthermore, it discusses the ethical, regulatory, and environmental considerations of using CRISPR for crop improvement, alongside its potential to revolutionize sustainable agriculture by reducing disease-induced yield losses and promoting food security.

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