Abstract
Crimean Congo hemorrhagic fever is a tick borne lethal zoonotic disease caused by Crimean Congo hemorrhagic fever virus belonging to the genus Nairovirus and Family Bunyaviridae. It contains Single stranded negative sense segmented RNA genome. The host range of CCFHV includes domestic as well as wild animals and birds. The incubation period of the disease varies from 3 to 13 days depending on the mode of transmission of disease, resulting in high grade fever, headache, dizziness, Photophobia, low blood pressure, muscle pain, vomiting, diarrhea, abdominal pain, hemorrhages, multi organ failure and death. No specific treatment is available so far, suspected cases are given supportive treatment and an antiviral agent Ribavirin. It is a global epidemic and was reported for the first time in Pakistan in 1976. Since 2000 sporadic cases have been reported in Pakistan mostly effecting Baluchistan and KP province due to the cross-border trade and migration of human beings and animals. Proper surveillance systems and guidelines need to be established to control and prevent the spread of disease. Keywords: Crimean Congo Hemorrhagic Fever; Epidemic; Pakistan http://dx.doi.org/10.19045/bspab.2020.90260
Highlights
Introduction encodes for RNA dependent RNACrimean Congo Hemorrhagic fever (CCHF)polymerase enzyme [6-9]
Pakistan is an endemic region for CCHF just like other countries of Asia such as Afghanistan, India, Iraq, Iran, Oman, Saudi Arabia, Kuwait, Dubai, Russia, China and many more [1, 2, 12]
Pakistan is an endemic area for CCHF, which is a highly contagious disease with a high mortality rate
Summary
Introduction encodes for RNA dependent RNACrimean Congo Hemorrhagic fever (CCHF)polymerase enzyme [6-9]. No specific treatment is available so far, suspected cases are given supportive treatment and an antiviral agent Ribavirin.
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