Abstract

 Cressa cretica (Shuwwayl) is a halophytic that belongs to Convolvulaceae, naturally grown in the Middle East including Iraq. Traditionally the plant is used as a paste for sore treatment, also it is used for fever, jaundice, and other illness. Regarding nonclinical use it is used as goat, sheep, and camel feed also as an oil source. Flavonoids including quercetin, kamepferol, apigenin, and their glycosides, phenolic acid as chlorogenic acid, and phytosterols mainly ?–sitosterol were the most important phytochemicals that were detected in this halophyte. Crude ethanolic, methanolic extracts and ethyl acetate fraction of the areal parts were used in clinical studies and demonstrated various effects as hepatoprotective, cytotoxic, and genotoxic effect. In molecular docking studies, 3,5-dicaffeoylquinic acid showed antiviral effect vs SARS-CoV-2 (sever acute respiratory syndrome corona virus-2). The purpose of this review was to clarify and discuss all aspects regarding Cressa cretica.
Highlights
Cressa cretica (Convolvulaceae)(1) is obligate halophytes which in demand for saline soil for its growth and development [2]C. cretica is a small dwarf branched shrub or subshrub typically has straight stems with white‐haired, green leaves [3]
Phenolic acids as 3,5 dicaffeoylquinic acid and chlorogenic acids were identified in the plant[38], protocatechuic (3,4-dihydroxybenzoic acid), p, gentisic acid (2,5-dihydroxy benzoic), chlorogenic, caffeic acid, vanillic acid,ferulic acid, sinapic (3,5-Dimethoxy-4- hydroxycinnamic acid), p-coumaric, gallic acid, and cinnamic acid were detected by HPLC in both ethanol and ethyl acetate extract of aerial parts
Mandeel et al (2005) showed the powerful inhibitory effect of ethanolic C. cretica extract against Penicillium citrinum followed by Candida albicans using agar diffusion method[52]
Summary
Cressa cretica (Convolvulaceae)(1) is obligate halophytes which in demand for saline soil for its growth and development [2]C. cretica is a small dwarf branched shrub or subshrub typically has straight stems with white‐haired, green leaves [3]. Non clinical uses of C. cretica This halophyte is considered suitable biodiesel due to high-level seeds oil contents besides good quality engine parameters. Kaempferol 3-O-β- glucoside (Astragalin) was isolated as the main glycoside in ethyl acetate fraction of ethanolic aerial parts extract in Iraqi plant[36]. Phenolic acids as 3,5 dicaffeoylquinic acid and chlorogenic acids were identified in the plant[38], protocatechuic (3,4-dihydroxybenzoic acid), p-, gentisic acid (2,5-dihydroxy benzoic), chlorogenic , caffeic acid, vanillic acid,ferulic acid, sinapic (3,5-Dimethoxy-4- hydroxycinnamic acid), p-coumaric, gallic acid, and cinnamic acid were detected by HPLC in both ethanol and ethyl acetate extract of aerial parts. In the fixed oil obtained from Egyptian aerial parts of cressa the majority of the detected fatty acids were unsaturated.
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Schedule a callMore From: Iraqi Journal of Pharmaceutical Sciences ( P-ISSN: 1683 - 3597 , E-ISSN : 2521 - 3512)
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