Abstract
Purpose: This article outlines the process of establishing the Trans Youth Care Research Network, composed of four academic clinics providing care for transgender and gender-diverse (TGD) youth. The Network was formed to design and implement research studies to better understand physiologic and psychosocial outcomes of gender-affirming medical care among TGD youth.Methods: Formed in response to both the Institute of Medicine's report recommendation for an increase of data concerning sexual and gender minority populations and a transgender-specific NIH program announcement, The Center for Transyouth Health and Development at Children's Hospital Los Angeles, the Gender Management Service at Boston Children's Hospital, the Child and Adolescent Gender Center Clinic at Benioff Children's Hospital in San Francisco, and the Gender and Sex Development Program at Lurie Children's Hospital of Chicago established a collaborative research network that subsequently designed a longitudinal observational study of TGD youth undergoing medical interventions to address gender dysphoria.Results: Two cohorts, youth starting puberty blockers and youth starting gender-affirming hormones, are participating. Psychosocial measures that span multiple domains of mental and behavioral health are collected from youth and parents. Physiologic data are abstracted from patient's charts. Baseline and follow-up data of this large cohort will be disseminated through conferences, abstracts, posters, and articles.Conclusion: Since initiation of funding in 2015, a total of 497 participants have been enrolled in TYC across the four sites; gonadotropin releasing hormone analogs (GnRHa) cohort youth (n=93), GnRHa cohort parents (n=93), and gender affirming hormone cohort youth (n=311). As the network moves toward data dissemination, its lessons learned have helped strengthen the current study, as well as inform future endeavors in this field.
Highlights
The psychosocial health of transgender and gender-diverse adolescentsAdolescence is a time of identity formation, during which youth are charged with exploration and growth, creating and pruning neural connections and pathways that are shaped by surroundings and experiences.[1]
Many health professionals have discarded the historical belief that transgender experience itself is pathological, replacing this ideology with an understanding that both gender dysphoria and the pervasive negative reactions from the environment are causal factors in the presenting mental health symptoms often evident among transgender and gender-diverse (TGD) individuals
In Western culture, gender development occurs within a cultural context of cisgender normativity. Within this cultural context, where there are few-to-no road maps for TGD youth to follow in exploring their gender, TGD youth are challenged with an additional burden: discovery, disclosure, and stigma management of a gender different from what has been assumed based on their sex designated at birth
Summary
The psychosocial health of transgender and gender-diverse adolescentsAdolescence is a time of identity formation, during which youth are charged with exploration and growth, creating and pruning neural connections and pathways that are shaped by surroundings and experiences.[1].
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