Abstract

A planar topology for a nanoelectronic transducer based on glucose oxidase is designed for use in an enzymatic biosensor. Electromigration is used to create 5-nm gaps in Au nanowires. A method for the chemical modification of a silica surface with epoxysilane is developed and glucose oxidase is immobilized on the surface of a support by means of linking molecules. A technique for biochemical signal registration is developed. The eelectric response of the biosensor with glucose in a test solution and the dependence of this response on the glucose concentration are investigated.

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