Abstract
ELEVATION of creatine kinase (CK) isoenzymes in patients with malignancies has been reported. The isoenzyme BB is commonly present in stage D prostate cancer but has also been reported in lung cancer of all histological types. This ectopic CK-BB may migrate to atypical positions on gel electrophoresis, depending on whether it forms complexes with immunoglobulins or other macromolecules. By contrast, the MB isoenzyme is rarely produced ectopically from carcinoma.<sup>1</sup>The patient described herein had a metastatic adenocarcinoma and a CK electrophoretic pattern on cellulose acetate that showed a normal MM peak with a larger peak anodal to the MM peak, in the position normally occupied by the CK-MB isoenzyme. <h3>Report of a Case</h3> A 66-year-old man was admitted to the Trumbull Memorial hospital with a two-day history of progressive dyspnea and pedal edema. Five months earlier, he had presented with pain in the right hip, weight loss, and a
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