Abstract
IN THE first study in this series (I) results were published showing that castration in both sexes of young adult white rats resulted in creatinuria which was more intense in the female than in the male. The injection of anterior pituitary hormones (G, T and S), theelin, follutein, and testosterone propionate, caused increases in muscle creatin and in creatin excretion accorripanied by decreases in creatinine excretion. The injection of all these hormones, with the exception of antuitrin‚S and T and of follutein, caused a more significant increase in the total amount of creatine excreted in the castrated rat than in the same rat before castration. A possible synergistic action of the hormones in the body upon creatine and creatinine metabolism was suggested. In the present study progestin and antuitrin-T, and theelol with antuitrin‚S, were injected into normal and castrated female rats. The experimental procedures were given in our first paper of this series (I).
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