Cream as a Drug Delivery System for Topical Diseases

Abstract

Creams are a type of pharmaceutical product used for daily skin care, as well as medicated and non-medicated applications. It is also regarded as a vital component of cosmetics. When the dosage form is creams, the route of delivery is the skin. The rate of medication absorption and penetration is influenced by a variety of factors in the skin. The topical medication delivery system is a method of delivering drugs to the skin. Topical medication administration has the advantage of bypassing first-pass metabolism, hydrating the skin, and providing emollient qualities. Creams are viscous or semisolid emulsions that come in O/W or W/O dosage forms and have a viscosity that changes depending on the quantities of oil and water in them. In terms of functions and qualities, there is a vast range of creams available. Pharmaceutical creams are used for a range of purposes, including cleansing, beautifying, hydrating, and protecting against bacteria and fungi, as well as treating skin wounds. Water, fats, waxes, emollients, colors, scents, and other common ingredients are employed in the creation of practically every cream, resulting in a standard formulation. There are various evaluation parameters available for creams which help the product to match its standard quality eg. pH, viscosity, stability, spreadability, etc.