C-reactive protein versus procalcitonin. Simillar but different biomarkers in the assessment of an infection

Abstract

Tyniec Mateusz, Lewicki Marcin, Morshed Kamal, Bojarczuk Katarzyna, Smolen Agata. C-reactive protein versus procalcitonin. Simillar but different biomarkers in the assessment of an infection. Journal of Education, Health and Sport. 2018;8(12):936-943. eISNN 2391-8306. DOI http://dx.doi.org/10.5281/zenodo.2621031 http://ojs.ukw.edu.pl/index.php/johs/article/view/6775 The journal has had 7 points in Ministry of Science and Higher Education parametric evaluation. Part b item 1223 (26/01/2017). 1223 Journal of Education, Health and Sport eISSN 2391-8306 7 © The Authors 2018; This article is published with open access at Licensee Open Journal Systems of Kazimierz Wielki University in Bydgoszcz, Poland Open Access. This article is distributed under the terms of the Creative Commons Attribution Noncommercial License which permits any noncommercial use, distribution, and reproduction in any medium, provided the original author (s) and source are credited. This is an open access article licensed under the terms of the Creative Commons Attribution Non commercial license Share alike. (http://creativecommons.org/licenses/by-nc-sa/4.0/) which permits unrestricted, non commercial use, distribution and reproduction in any medium, provided the work is properly cited. The authors declare that there is no conflict of interests regarding the publication of this paper Received: 03.11.2018. Revised: 10.12.2018. Accepted: 30.12.2018. C-reactive protein versus procalcitonin. Simillar but different biomarkers in the assessment of an infection Mateusz Tynieca, Marcin Lewickia, Kamal Morsheda, Katarzyna Bojarczuka, Agata Smolena aChair and Department of Epidemiology and Clinical Research Methodology of the Medical University of Lublin, ul. Radziwillowska 11, Lublin 20-080, Poland; mateusztyniec@yahoo.com; 0000-0002-0191-319X; lewicki-marcin@wp.pl; 0000-0003-1906-9326; kamal1@op.pl; 0000-0003-0061-0362; agatasmolen@umlub.pl; 0000-0003-0764-6667; ABSTRACT: Markers of systemic inflammation and bacterial infection such as C-reactive protein (CRP), and procalcitonin are commonly evaluated parameters in everyday medical practice. They are useful in quick assessment of patients condition, and the utility of CRP and procalcitonin as a marker of infection has been confirmed. An ideal marker of an inflammatory reaction should take into account many features. It should be remembered that we can not always choose one, more valuable biomarker. Interpretation of the results depends on numerous factors such as clinical status, weight and age. Both markers have their limitations. Early inflammatory disease diagnosis, properly implemented effective antibiotic therapy can contribute to the reduction of mortality. Keywords: C - reactive protein, procalcitonin, inflammatory response, infection