C-Reactive Protein Serum Levels In Rhabdomyolysis Patients

Abstract

Introduction: We hypothesized that Rhabdomyolysis might be associated with elevated C-reactive protein (CRP) serum levels.Methods: We reviewed the medical charts of five Rhabdomyolysis patients in whom CRP and creatine phosphokinase (CPK) serum levels had been measured together day by day, and in whom myocardial infarction and/or systemic infection had been excluded as well.Results: Mean age of Rhabdomyolysis patients was 41.8±13.6 years. Rhabdomyolysis patients had mean maximal CPK and CRP serum levels of 14610±14346 U/L and 57.7±55.1 mg/L, respectively. CRP serum levels velocity paralleled CPK serum levels velocity among all patients. CRP serum levels significantly correlated with CPK serum levels (r=0.53, p=0.005).Conclusions: CRP serum levels are elevated in Rhabdomyolysis patients and are correlated with CPK serum levels. CRP serum levels may be measured together with CPK serum levels in order to monitor the inflammatory process associated with Rhabdomyolysis.