Abstract
To the Editor: Sano et al1 investigated the relation between lesion morphology as seen under preintervention intravascular ultrasound and C-reactive protein (CRP) in the acute phase of acute myocardial infarction (AMI). They found that elevated CRP concentrations may be related to the presence of ruptured plaque and concluded that in the setting of AMI, elevated CRP levels may reflect the inflammatory activity of a ruptured plaque. The presence of inflammatory infiltrates in unstable coronary plaques suggests that inflammatory processes may contribute to the pathogenesis of acute coronary syndromes.2 In patients with acute coronary syndromes, coronary atherosclerotic plaques are characterized by the presence of macrophages and, to a …
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