Abstract

Craniosynostosis is a developmental craniofacial anomaly, resulting in impairment of brain development and abnormally shaped skull. The main cause of craniosynostosis is premature closure of one or more cranial sutures. It usually occurs as an isolated condition, but may also be associated with other malformations as part of complex syndromes. When left untreated, craniosynostosis can cause serious complications, such as developmental delay, facial abnormality, sensory, respiratory and neurological dysfunction, anomalies affecting the eye, and psychological disturbances. Thus, early diagnosis, expert surgical techniques, postoperative care, and adequate follow-up are of vital importance in treating craniosynostosis.

Highlights

  • The cranial vault develops from the mesenchymal tissue

  • A craniosynostosis is a developmental anomaly which occurs as a consequence of abnormal and non-physiological sutural fusion

  • ‐ Premature fusion of the coronal suture ‐ Forehead flattened on the affected side ‐ High supraorbital margins (Harlequin sign) ‐ Forehead pushed forward on the unaffected side ‐ Nasal septum deviation towards the normal side ‐ More common in girls (2:1)

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Summary

Introduction

The cranial vault develops from the mesenchymal tissue. This may result in a premature fusion of one or more sutures, which is called craniosynostosis [5,8]. A craniosynostosis is a developmental anomaly which occurs as a consequence of abnormal and non-physiological sutural fusion.

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