Abstract
Reported: Serum CPK levels were estimated in nine cases of motor neuron disease. They were elevated in one case of Kugelberg-Wellander's disease and in one case of ALS which had rapidly developed to result in a widespread muscle atrophy of the trunk and extremities.On the other hand, an autopsy case of ALS, which had developed slowly during the five years following onset, showed no elevation in serum CPK. In the literature, elevation has been reported in some cases of motor neuron diseases.Discussed: The latter two findings suggest that the CPK level might be related to the speed of the progression of muscle atrophy during the disease course. Then again our case of Kugelberg-Wellander's disease, which differs from other motor neuron diseases in its coexistence of myogenic changes with neurogenic ones, showed a high CPK level; this finding might afford a clue to diagnosis.
Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
