Abstract
Abstract CpG is the pair of nucleotides C and G, appearing suc-cessively, in this order, along one DNA strand. It is known that due to biochemical considerations CpG is relatively rare in most DNA sequences. However, in par-ticular subsequences, which are a few hundred to a few thousand nucleotides long, the couple CpG is more frequent. These subsequences, called CpG islands, are known to appear in biologically more significant parts of the genome. The ability to identify CpG islands along a chromosome will therefore help us spot its more sig-nificant regions of interest, such as the promoters or 'start' regions of many genes. In this respect, I devel-oped the CpG islands search tool, CpG Islands Detector, which was implemented in JAVA to be run on any platform. The window-based graphical user inter-face of CpG Islands Detector may facilitate the end user to employ this tool to pinpoint CpG islands in a ge-nomic DNA sequence. In addition, this tool can be used to highlight potential genes in genomic sequences since CpG islands are very often found in the 5' regions of vertebrate genes.Availability: The tool is available free of charge for non-commercial use only. Contact the corresponding authorKeywords: CpG island, promoter, CpG islands detector, JAVA, graphical user interface
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