Abstract
Coxsackieviruses are divided into two groups (A and B) based largely on their pathogenicity and replication in newborn mice. Both groups have been associated with a wide variety of neurological, cardiovascular, gastroenteric, ophthalmic, and exanthematic diseases. The main natural hosts of coxsackieviruses are humans but several studies have established that coxsackievirus B5 (CVB5) and swine vesicular disease virus (SVDV) are antigenically closely related.
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