Abstract

The relationship of cardiovirulence in mice (HAM/ICR, Swiss ND-4) of four coxsackievirus B4 strains to previously described in vitro markers (t, d, DS, DEAE-D, G, PS) has been determined. A relationship between plaque size and acardiovirulence was demonstrated in the HAM/ICR coxsackievirus B4 mouse system.

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