Abstract

To the Editor: We have previously reported the seroprevalence of 3 common atypical respiratory pathogens, Chlamydia pneumoniae , Mycoplasma pneumoniae , and Legionella pneumophila , in case-control studies involving an elderly cohort of stroke/transient ischemic attack (TIA) and medical patients.1 We concluded that the risk of stroke/TIA appeared to associate with the aggregate number of chronic infectious burden of these atypical respiratory pathogens.1 We have now determined the seroprevalence (immunoglobulins, IgG and IgM) of Coxiella burnetii , another well-recognized atypical respiratory pathogen in this same cohort of patients. Using commercial enzyme-linked immunosorbent assay (ELISA) kits (PANBIO Ltd), the seropositivity of Coxiella burnetii IgG was found in 2 (2.4%) out of the 85 ischemic stroke/TIA …

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