Abstract

Cow's milk protein allergy (CMPA) frequently occurs in the first year of life, with a prevalence of 23% in the infant population. Food protein-induced enterocolitis syndrome (FPIES) is a severe non-IgE (immunoglobin E) presentation—mediated food allergy, which CMPA frequently causes. FPIES is frequently misdiagnosed initially due to its non-specific symptoms and laboratory findings. We present a case of a three-month-old male infant with allergic colitis due to CMPA. The patient was initially diagnosed with infectious colitis, which was then found to be allergic. The patient also did not tolerate extensively hydrolyzed formula and needed amino acid formula. The patient was discharged home in a stable condition. This research implies an increase in awareness and health education among parents, especially those with young infants. The findings of this study can also have an impact on changes in healthcare services and encourage the development of substitute milk products more suitable for infants with cow's milk protein intolerance.

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