Abstract

Abstract: Stevens-Johnson syndrome (SJS) is an acute inflammatory vesiculobullous reaction of the skin and mucosa. The involvement of the ocular mucosa in these cases leads to ocular SJS. The most commonly reported etiological agents for SJS are drugs, viral infections, and vaccination. Here, we present the first ever reported case of ocular SJS occurring secondary to COVISHIELD vaccination, wherein a 62-year-old had an episode of acute SJS within a week of the COVISHIELD booster dose. She presented to us 6 months after the acute episode with infectious keratitis in the right eye and descemetocele in the left eye in chronic SJS with severe bilateral lid keratinization in all 4 lids and healed skin pigmentation typical of SJS sequelae.

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