Abstract
Background/Aim: The recent pandemic of Severe Acute Respiratory Syndrome Corona Virus-2 (SARS-CoV-2) is yet another scourge from the coronaviridae family that causes illnesses ranging from common cold to more severe diseases such as Middle East respiratory syndrome (MERS-CoV) and severe acute respiratory syndrome (SARS-CoV). The numbers are still on the rise, despite a country wide lockdown and yet no definitive drugs and or/vaccines are available to manage the active COVID-19 cases. Methods: The present research design was a hospital based observational descriptive study conducted at S. M. S. Medical College and Attached hospitals, Jaipur, that analysed data of all the patients with COVID-19 related mortality, admitted between 1 April to 4 May 2020. Patients included in this study were RT-PCR confirmed cases of SARS-CoV-2 using nasopharyngeal and oropharyngeal swab samples. Results: The mean age of patients with COVID-19 related mortality was 53.41 ± 18.42 year with majority of patients belonging to age group of more than 60 years (41.18 %) followed closely by COVID-19 positive patients in age range of 45 to 60 years (33.33 %). The male to female ratio was 1.68: 1. Mean time lag between hospitalization and death reported was 6.18 days. Majority of the patients admitted (72.5 %) succumbed within 3 days of hospitalization. Eleven patients (21 %) were brought dead to the hospital who were tested COVID-19 positive after death. Most common comorbidity reported in patients with COVID-19 related mortality was hypertension (30 %) followed by diabetes mellitus (27.5 %). Conclusion: Hypertension and diabetes mellitus might be independent risk factors making an individual susceptible to COVID-19 related death. Elderly patients also have a greater risk of mortality. The non-availability of definitive management protocol and/or vaccine against COVID-19 makes public health preventive measures of social distancing, use of masks and frequent handwashing an important modality in the fight against COVID-19.
Highlights
The recent pandemic of Severe Acute Respiratory Syndrome Corona Virus-2 (SARS-CoV-2) known as Corona Virus Disease 2019 (COVID-19) is yet another scourge from the Coronaviridae family that causes illnesses ranging from common cold to more severe diseases such as Middle East respiratory syndrome (MERS-CoV) and severe acute respiratory syndrome (SARS-CoV)
The present study, a hospital based observational descriptive study, was conducted at SMS Medical College and attached hospitals, Jaipur, sharing the highest load of patients in the Rajasthan that analysed and evaluated data of all COVID-19 related mortality of patients admitted between 1 April to 4 May 2020
Patients were categorised into five different age groups to evaluate the relation between age and COVID-19 related mortality
Summary
The recent pandemic of Severe Acute Respiratory Syndrome Corona Virus-2 (SARS-CoV-2) known as Corona Virus Disease 2019 (COVID-19) is yet another scourge from the Coronaviridae family that causes illnesses ranging from common cold to more severe diseases such as Middle East respiratory syndrome (MERS-CoV) and severe acute respiratory syndrome (SARS-CoV). The current pandemic of COVID-19 has affected 215 countries, areas, or territories worldwide as of 8 May 2020, and has infected 3,822,382 people worldwide, causing 263,658 confirmed deaths.[1] The spread of COVID-19 began from Wuhan, a city of Hubei province of China and was declared a pandemic by World Health Organization (WHO) on 11 March 2020.2. India has been struggling to contain the spread of virus and has managed to flatten the curve at 41,472 active cases and 2,109 deaths as of 10th May 2020, since the first reported SARS-CoV-2 case on 30 January 2020.5 The numbers are still on the rise, despite a country wide lockdown with yet no definitive management protocol inclusive of drugs and or/vaccines available to manage the active COVID-19 cases. The present study was undertaken to appreciate and describe mortality profile of SARS-CoV-2 at one of premier Institute of Tertiary Care Medical College of Rajasthan and SouthEast Asia
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