Abstract
COVID-19 related lung pathology: old patterns in new clothing?
Highlights
Menter et al report a cohort of 21 patients dying of COVID-19 infection
The identification of vascular lung pathology in some, but not all, patients is consistent with clinical and imaging data in relation to pro-thrombotic states,[7,8] and we can conceptualise that this breadth of pathology findings represents several pathways through which patients, especially those who suffer severe disease, progress to a final common outcome of diffuse alveolar damage (DAD)
This is seen in other reports,[2,4,13] and is in keeping with some patients at autopsy reported by Menter et al, whereas a relative dearth of lymphoid infiltrate is reported in other cases.[1]
Summary
Menter et al report a cohort of 21 patients dying of COVID-19 infection. Acute lung injury was the main pathology at autopsy, primarily showing the exudative phase of diffuse alveolar damage (DAD), with a minority displaying the organising (or proliferative) phase.[1].
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