Abstract
Occurrence and recurrence of COVID-19 cases have been observed globally. The complex relationship of host-pathogen and the environment plays a vital role in understanding the widespread recurrence of the SARS-CoV-2 among humans. Though the pathobiology of the disease is not completely understood, it is well established that COVID-19 poses a greater threat to individuals with co-morbidities and a weakened immune system. The article deals with the notion of innate immunity, natural selection, and the survival of the fittest during the COVID-19 outbreak. The article also attempts to introduce the concept of "lifestyle and cultural immunity" that needs to be addressed and incorporated at an early stage of childhood to boost up the human immune system. The communication further discusses the role of vaccination and micro-organisms pre-existing in the environment which are required to enhance the immunity of an individual.
Highlights
Since the beginning of the COVID-19 (Coronavirus disease 2019) pandemic, SARS-CoV-2 (Severe acute respiratory syndrome coronavirus 2) has infected about 230 million people, and caused more than 4 million deaths
Diffusion of viruses from one species to another is not unusual, evolutionary changeover is a rare event which might happen after millions of mutations and adaptations to those viruses; and SARS-CoV-2 may be a paradigm of a successful evolutionary changeover [9]
The individuals whose immune system can combat the novel coronavirus are less affected compared to the others; thereby, achieving the innate immunity by restricting the replication of viral cells and triggering adaptive immune responses
Summary
Introduction Since the beginning of the COVID-19 (Coronavirus disease 2019) pandemic, SARS-CoV-2 (Severe acute respiratory syndrome coronavirus 2) has infected about 230 million people, and caused more than 4 million deaths. The primary source of this viral infection is still unknown, its genetic sequence is assumed to be similar to that of SARS-CoV-1 and MERS (Middle East respiratory syndrome).
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