COVID-associated rhinocerebral mucormycosis: a retrospective analysis of presentation and outcomes.

Abstract

ObjectivesTo comprehensively analyse the disease presentation and mortality of COVID-associated rhino-orbito-cerebral mucormycosis.MethodsA retrospective analysis of the demographics, clinical and radiographic findings was performed. A binary logistic regression analysis was performed to examine the survival of patients with mucormycosis from hypothesised predictors.ResultsA total of 202 patients were included in this study. Statistical significance was demonstrated in the predilection to the male gender, recent history of SARS-COV-2, history of use of corticosteroid and hyperglycemia in this cohort of CAM. The mortality rate was 18.31%. Advanced age, raised HbA1c and intra-orbital extension were found to be predictors adversely affecting survival.ConclusionEarly diagnosis, aggressive surgical therapy, early and appropriate medical therapy can help improve outcomes.Level of evidenceLevel 4.