Abstract
<br><b>Aim:</b> The aim of this study was to analyze the viral clearance patterns in COVID-positive patients with kidney disease. <b>Patients and Methodology:</b> This is a single-center observational study with demographic and clinical details of all the patients with renal insufficiency referred for COVID infection management. <b>Results:</b> Of total admissions of 250 patients with renal insufficiency, data were analyzed in those who were discharged from the hospital. Of 250 patients, 108 died and the data of 142 patients were analyzed. The mean duration of viral clearance was 27.5 days, with a range being <3 weeks to 45 days. The mean number of days for viral clearance in acute kidney injury (AKI) was 22.5 days, chronic kidney disease (CKD)-5D was 25.2 days and in transplant recipients 23.4 days. The maximum number of patients cleared the virus in the 4<sup>th</sup> week and near-complete viral was achieved by the end of the 6<sup>th</sup> week. Factors such as age, type of renal insufficiency such as AKI/CKD, presence of comorbidities like diabetes, severity of COVID disease, and presence of multiorgan involvement were not associated with viral clearance. <b>Conclusion:</b> In patients with kidney disease, weekly viral clearance was maximum in the 4<sup>th</sup> week. Moreover, cumulative viral clearance was 99% by the end of the 6<sup>th</sup> week.<br>
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