COVID-19 Tanısı Alan Yaşlı Bireylerde Aşıların Etkinliği: Retrospektif Kesitsel Bir Çalışma

Abstract

Objective: This study aimed to determine the effectiveness of vaccination status and vaccine types on the course and outcomes of the disease in the older individuals diagnosed with coronavirus disease-2019 (COVID-19). Material and Methods: The study included 1,258 individuals aged 65 years and older who were diagnosed with COVID-19 [polymerase chain reaction (PCR) test positive] between February and March 2022, and the study was conducted retrospectively. The vaccination status of the individuals, the types of vaccines administered to the individuals, and the number of vaccines were obtained from the Vaccine Tracking System. PCR results, hospitalization, and rates of death were obtained from the Public Health Management System. Results: Over 80 years of age was identified as a significant risk factor. In patients vaccinated with at least one dose of mRNA, the rate of intensive care unit treatment was 1%, and the rate of exitus was 0.2%. While 14% of individuals who had never been vaccinated were treated in the intensive care unit, all of these individuals became exitus. Among individuals vaccinated with at least 2 doses of inactivated vaccine, 6.4% were admitted to the intensive care unit, while 5% became exitus. It was determined that patients who received at least one dose of the mRNA vaccine were 93% protected from the need for intensive care and 99% protected from death. Conclusion: In terms of public health policies, appropriate vaccination, planning, and implementation of booster doses after vaccination are the most effective methods to protect older people from COVID-19.