COVID 19 Radiological Severity and Its Correlation with Complete Blood Picture Indices

Abstract

Abstract Background The International Committee on Taxonomy of Viruses (ICTV) named this novel coronavirus as SARS-CoV-2. This infection is still spreading but now less than before, and this virus poses a serious threat to public health, though joint prevention and quarantine mechanisms in almost all provinces of mainland China have been confirmed to be enacted. Due to a lack of specific antiviral treatments and pressure of clinical treatment, thousands of severe cases have died every day worldwide. Our university isolation hospitals as a part from the Egyptian isolation hospitals were in the first line in facing this epidemic. Objectives This work was to investigate the radiological severity in COVID 19 patients and its correlation with complete blood picture indices among a sample of Egyptians. Patients and method This was an observational, analytical & prospective study, recruited 30 cases of COVID 19 patients admitted to Ain Shams University isolation Hospitals. All patients were confirmed to be COVID 19 positive by PCR. Through history taking and clinical examination was done. On admission CBC and CT chest were documented analyzed and correlated. Result 30 COVID 19 patients were recruited with 60% of them were mals, 66% have no comorbidities. Their ages were 54.833± 13.097 ranging from 25 to 85 years old, their most distressing symptom was dyspnoea (53%). Their radiological probability of CT chest were CORADS 5, CORADS 4 and CORADS 3 representing (63.33%, 23%.33, 13.33%) respectively. Almost more than 4/5 (83.33%) of them were admitted in the ward. All patients admitted in the ICU died (16.67%). A highly significant decrease in absolute lymphocytic count with the increase in the degree of probability of CT chest (CORADS degree) with (P value less than 0.001). Also a significant decrease in absolute monocytic count with the increase in the degree of probability of CT chest (P value 0.015). No other CBC indices were found to be have any significant correlation with CT chest severity or probability scoring. A cutoff value of 1.16 thousand /ml or less for lymphocytes and 0.4 thousand /ml or less for monocytes can predict CT chest to be CORADS 5. Conclusion A strong association with lymohocytic and monocytic count of the complete blood picture of COVID 19 patients with the radiological probability of CT chest.