Abstract

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 Bangladesh Journal of Medical Science Vol.20(2) 2021 p.221-227

Highlights

  • “It is not difficult to make microbes resistant to penicillin in the laboratory by exposing them to concentrations not sufficient to kill them, and the same thing has occasionally happened in the body 1.” Sir Alexander Fleming

  • The development of AMR pathogens and their dispersal throughout the planet are the consequences of several years of constant selection pressure from human, especially health professionals irresponsible use of antimicrobials through imprudent use, 11-18 poverty, 19-21 poor sewage clearance setup, 22-24 profound escalation of international travel 25, 26, and better healthcare access for progressively more marginalized communities without any regulatory control often increases the imprudent use of antibiotics (Figure 1) 13, . 27-29 In this miserable background, the current global pandemic of COVID-19 impacts the antimicrobial consumption and increases the selection pressure of appropriate antimicrobials to curb the additional impending burden of antimicrobial resistance during this pandemic is yet to be determined 27, 30, 31

  • Multiple studies have reported that a high quantity of broad-spectrum antimicrobials are prescribed and consumed among COVID-19 patients 13, . 30-35 in many low and middle countries (LMICs), the antimicrobials are available over the counter 36, 37

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Summary

Introduction

“It is not difficult to make microbes resistant to penicillin in the laboratory by exposing them to concentrations not sufficient to kill them, and the same thing has occasionally happened in the body 1.” Sir Alexander Fleming. World Health Organization (WHO) reported that there had been 96,658,420 confirmed cases of COVID-19, including 2,092,062 deaths, till January-23-2021 2. Multiple studies have reported that a high quantity of broad-spectrum antimicrobials are prescribed and consumed among COVID-19 patients 13, .

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