COVID-19 pandemisi ve COVID-19 aşısının menstrüel siklusa etkisi

Abstract

Effect of COVID-19 pandemic and COVID-19 vaccine on menstrual cycle Menstrual cycle irregularities include changes in menstrual cycle frequency, regularity, duration or intensity, as well as breakthrough bleeding. The global prevalence of irregular menstrual cycle ranges from 5% to 34% during reproductive years, and related problems constitute one of the most common reasons for referral to a gynecologist. It has been stated that during the Covid-19 pandemic and after the covid-19 vaccines, menstrual irregularities increased and the number of pads decreased in women. If these changes are related to the vaccine, it is thought that it may be a result of the immune response to the vaccine rather than a specific vaccine component. While reported changes in menstrual cycle after vaccination are short-lived, robust research on this potential adverse reaction remains critical to the overall success of the vaccination program. While Covid-19 affects social life, women cause hormonal imbalances, especially during the sexually active period. As a result, menstrual cycle irregularities may result in a decrease in the number of pads used and result in a decrease in the number of population that will threaten future generations. The aim of this study was to investigate the effects of mRNA vaccine and adenovirus vectored vaccines developed as Covid-19 pandemic and Covid-19 vaccine between December 2019–2022, the beginning of the pandemic process, on hormonal disorders and menstrual cycle irregularities. Resources were accessed from the literatures PUBmed, Web of Science, Google Academic using the keywords “Covid-19 pandemic, Covid-19 vaccine, menstruation, menstrual cycle irregularity” and 14400 references were identified. The number of retrospective studies and case reports were excluded, and the number decreased to 30, and 20 of the appropriate scientific publications were included in the study by scanning the rest. Keywords: Covid-19 pandemic, Covid-19 vaccine, menstruation, menstrüel cycle irregularity