Abstract

The recent global health problem, COVID-19, has had far-reaching impacts on lifestyles. Although many effective WHO-approved vaccines have been produced that have reduced the spread and severity of the disease, it appears to persist in humans for a long time and possibly forever as everyday it turns out to have new mutations. COVID-19 involves the lungs and other organs primarily through cytokine storms, which have been implicated in many other inflammatory disorders, including periodontal diseases. COVID-19 is in a close association with dental and periodontal practice from two respects: first, repeated mandatory lockdowns have reduced patient referrals to dentists and limited the dental and periodontal procedures to emergency treatments, whereas it is important to recognize the oral manifestations of COVID-19 as well as the influence of oral and periodontal disease on the severity of COVID-19. Second, dentistry is one of the high-risk professions in terms of close contact with unmasked individuals, necessitating redefining the principles of infection control. The pressures of the economic recession on patients as well as dentists add to the difficulty of resuming elective dental services. Therefore, this study is divided into two parts corresponding to what mentioned above: the first part examines the clinical and immunological associations between COVID-19 and periodontal and oral diseases, and the second part delineates the measures needed to control the disease transmission in dental clinics as well as the economic impact of the pandemic era on dental services.

Highlights

  • Since its outbreak in Wuhan, China, the coronavirus disease of 2019 (COVID-19) turned to a new global concern, taking millions of lives

  • Patients with severe forms of COVID-19 and periodontitis have been reported to suffer from elevated serum levels of several cytokines

  • IL-6 has been found to have similar countless functions in the pathogenesis of the cytokine storm associated with both periodontitis and COVID-19, supporting the possible links between these two diseases

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Summary

Introduction

Since its outbreak in Wuhan, China, the coronavirus disease of 2019 (COVID-19) turned to a new global concern, taking millions of lives . Research suggests that there exists an association between COVID-19 and periodontal diseases as they both show similar proinflammatory cytokine release and affect the systemic health [2]. The present study is aimed at evaluating the mutual relations between the periodontal diseases and COVID-19 and reviewing the immunological, clinical, and practical considerations for dental practitioners. It discusses how repeated lockdowns followed by the economic recession have considerably restricted [3] and reduced the demand for dental services including periodontal and dental implant therapies mostly considered as nonemergency treatments

The Virus and the Disease Pathophysiology
Immunologic Links between COVID-19 and Periodontitis
COVID-19 in Periodontal Patients
Oral Manifestations of COVID-19
Protection against COVID-19 Pandemic Using Periodontal Treatments
Economic Implications
Findings
Conclusion
Full Text
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