Abstract
Background:SARS CoV-2 has globally affected more than 31 hundred thousand population with more than 2 hundred thousand deaths till date, since its inception from Wuhan, China in December 2019. World is still clueless regarding definitive treatment for this highly contagious disease. Till then we have to rely on time tested methods to delay/stop transmission of this viral disease by observing social isolation, hand hygiene and wearing face mask.Objective:The main objective of this review paper is to focus on different modes of transmission of this virus, comparison of this virus with previous similar analogy viral diseases like SARS and MERS and different strategies that can be planned or are ongoing to reduce/delay transmission of this virus in community contacts, especially in context to India.Methods:PUBMED, Google Scholar and BioRxiv search was performed with keywords; COVID- 19, mode of transmission, infection, India, BCG. Around 538 eligible papers were evaluated from time period of January 1 to 29 April 2020 and results were summarizedResults:On analysis of different papers on mode of transmission it was found that this virus is highly contagious and spreads through air droplet, close contact, through fomites and different metallic surfaces and through aerosol in surroundings with high aerosol generating procedures only. Also, it can spread both in asymptomatic and symptomatic phase equally so early testing is essential. Also, it is mutating in different host environments so it is imperative to include different strains in vaccine preparation.Conclusion:Results demonstrate the fact that early screening, social distancing, isolation of symptomatic patients, respiratory etiquette are the main armaments presently to deal with this virus till effective treatment or vaccine becomes available in the near future. Furthermore, we would like to suggest the Indian government to create a National Viral Disease Management Board on lines of National Tuberculosis Elimination program to prevent and control such viral outbreaks in future.
Highlights
A virus is defined by its genomic sequence that can autonomously replicate inside cells and can transmit between cells or organisms under appropriate conditions and may or may not cause the disease [1]
This paper intends to highlight the difference in mode of transmission of SARS CoV-2 from SARS CoV and MERS and whether these differences play some role in more widespread infection by SARS CoV-2 virus and the strategies that can be adapted to delay/stop transmission with special reference to India
In controlled experimental settings only, it was found in aerosol ; so it is assumed that only aerosol generating procedures like nebulization, bronchoscopy, suctioning, endotracheal intubation, mechanical ventilation,etc can lead to aerosol transmission [23, 24]
Summary
The main objective of this review paper is to focus on different modes of transmission of this virus, comparison of this virus with previous similar analogy viral diseases like SARS and MERS and different strategies that can be planned or are ongoing to reduce/delay transmission of this virus in community contacts, especially in context to India
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