COVID-19 NA INFÂNCIA: uma revisão

Abstract

Objective: To review all pre-selected publications on COVID-19 cases in the pediatric population and to formulate an organized synthesis addressing fundamental and specific points of the disease performance in children. Data sources: We used a crossover of keywords “COVID-19” and “child care", to search scientific publications in the Virtual Health Library in the data bases: LILACS, BVS, PubMed, and Scielo. Wethen selected publications that: 1) relevance, 2) addressed the theme of coronavirus infection mainly in childhood; 3) elucidated clinical particularities of COVID-19 in the child population; and 4) were published either in English or Portuguese. We excluded all publications that had conflicts of interest and those that were not available in full. Summary of the data: We identified 2,262 publications based on our keywords search which only 38 of them met the selection criteria for our analyses. Studies registered different patterns of COVID-19 infections in childhood when compared to adults, with less aggressive manifestations. However, studies report that infected children and young people symptoms can have serious complications with manifestation of multisystemic inflammatory syndrome, characterized by the late occurrence of vasculitis similar to Kawasaki's syndrome, incomplete Kawasaki's and / or toxic shock syndrome. Conclusions: Overall, epidemiology indicates a lower rate of contamination and a lower number of cases with severe outcomes in the pediatric population. However, the potential for transmissibility and the factors that determine serious outcomes in the pediatric population are still uncertain, which calls for greater investments so we can best protect and serve our upcoming generations.