Abstract

Survey of actual literature and scientific reports was made. The most substantial analytical and diagnostical methods were identified and described. Principles and limitations of the methods are described, and actual papers are cited in this review. Analytical and diagnostical methods like Polymerase Chain Reaction (PCR), Loop-mediated isothermal Amplification (LAMP), Lateral Flow Immunochromatography Assay (LFIA), Enzyme-Linked Immunosorbent Assay (ELISA), biosensors and ChemiLuminescence ImmunoAssay (CLIA) are discussed for assay of viral particles, antigens and specific host antibodies in blood, serum, plasma, nasopharyngeal swab and other samples in order to diagnose COVID-19. The Coronavirus Disease 2019 (COVID-19) is an emerging disease that has spread over the world since the end of year 2019. The global epidemic pointed at the necessity to introduce sensitive methods for instrumental diagnosis of COVID-19 and distinguishing it from the other viral diseases. (Tab. 2, Ref. 96).

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